Totally blind mice get sight back

Totally blind mice get sight back
Totally blind mice get sight back
Totally blind mice get sight back
Totally blind mice get sight back

Totally blind mice have had their sight restored by injections of light-sensing cells into the eye, UK researchers report.

The team in Oxford said their studies closely resemble the treatments that would be needed in people with degenerative eye disease.

Similar results have already been achieved with night-blind mice.

Experts said the field was advancing rapidly, but there were still questions about the quality of vision restored.

Patients with retinitis pigmentosa gradually lose light-sensing cells from the retina and can become blind.

The research team, at the University of Oxford, used mice with a complete lack of light-sensing photoreceptor cells in their retinas.Themice were unable to tell the difference between light and dark.
Reconstruction

They injected “precursor” cells which will develop into the building blocks of a retina once inside the eye. Two weeks after the injections a retina had formed, according to the findings presented in the Proceedings of the National Academy of Sciences journal.

Prof Robert MacLaren said: “We have recreated the whole structure, basically it’s the first proof that you can take a completely blind mouse, put the cells in and reconstruct the entire light-sensitive layer.”

Previous studies have achieved similar results with mice that had a partially degenerated retina. Prof MacLaren said this was like “restoring a whole computer screen rather than repairing individual pixels”.

The mice were testedtoseeiftheyfledbeingin

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